A clinical study for patients with proteinuria (high protein in your
urine) and chronic kidney disease (CKD)
APOL1-medicated kidney disease is a type of chronic kidney disease
caused by a substance in our body called the APOL1 protein (also
known as the apolipoprotein L1). This variant of APOL1 is more
likely to occur in people of African ancestry. African ancestry
includes people who identify as African American, Black,
Caribbean, Sub-Saharan African, and Latino (Cuban, Mexican,
Puerto Rican, or South or Central American).
Genetic testing is used to check differences in people’s DNA. A doctor
takes a small blood sample and saliva sample, and sends them to a
laboratory to be tested. If you decide to take part in the AMPLITUDE
clinical research study, you will be asked to provide consent for your
study doctor to perform a test, to see if you carry the variant of the
APOL1 protein being researched in the study. This test is
investigational and is not approved by health authorities, which means
that it is not available outside of a clinical research study. If you would
like to discuss the test more, or if you would like to understand what
the results of your test mean, an appointment can be made with a
genetic counselor (at no cost).
For more details or to see if you qualify for a clinical, please contact the office
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